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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3b7653bca24a0d05ead8977cf6a9f2f9a06791b4732aa48c8df9883669c04d8' 
  AND token = 'Jzk5HZ/iAXfd3hOtUzOkxY/zAOhrMA53tFH8NPVVc7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}