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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b3205f045792ac3b202cbf8d7eb70e64d35076ac56784e04cb9ee71e4ea0cc' 
  AND token = 'im8OW26Xhlo/2Uz18Ydg6PqVwScHDUQOR07EhS3Ml54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}