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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b48276f9a29834d22ae8a4b64f58920b26786b03d630db5331dc1c14e4013594' 
  AND token = 'mHMmksxjbUlVCxfcIDlnC/mM/xWXYvTIG4Gp5Y2DU9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}