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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdf3cbcb4f565b3c544af23f201484b68ae2b5c6533eea4b54ce979b233b619d' 
  AND token = 'T2s0KMFE8k+kqwElpcvX9eBND3zTiauXE52nV8oCDHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}