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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c4f6c06ca09c4157945dff44572c5dc258791072ce03508ab3b3615cf2cef6f' 
  AND token = 'duZ+UvMMab0/wDBPkShxO8VF0ASCcAfKt10dY7ey9FI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}