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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f38e5dcbb17ba9ad921766a7231599711f4c5aa1a06ff98b80c6ea9ce90245f2' 
  AND token = 'z1lt+eEZyy4HzU0mSjae06z2eLIXfeW80kK4KUJpOJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}