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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86a387aa2dde66cb4e00598d072de578e3c3b299de3b5db183b74621769f7dfc' 
  AND token = 'UV48/lPtkHZMMDCeV7nVAqG4MDT9x09RmajSyrm8CEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}