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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb5b49226985d0423044c927ef0474e25fc7477307538a46b3b9570d4a8d3e8d' 
  AND token = 'G2M9QX/Ttrd7aOXLkJULnzFTlRZX9eVzM5dSgg7gClw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}