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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1401c038282a2b7d990099849e43dfd95e3c59e56ffa57eeb1bf806f6e4be635' 
  AND token = 'ld4v0uzrKy/5RPCw+QAdilAnXAF94lt+BFkGUjaHLdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}