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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '545886c7d036d7f456b13a1ed30ef59712659e68910643a1421d7a325dd56f75' 
  AND token = 'qj7YT7xoyXBq1m4BbD5yMlMCN0kUIcivXnL8GtlKosc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}