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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5843446f1f169b82b3dfc43c80b4c86f6dd115b737979492e9df55ddfc13627' 
  AND token = 'MseDNLVglIch1mSlZI2DqbyotP5Fuj5/wIE9oB6Z0do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}