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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac2c5d01f37e21ed18f1d24b8f75e6a9d01d9a88510a98bd571d8d601fa26234' 
  AND token = 'CDSyxq9URLQAdO11CH44OPHsbokXQhhn4dPnHaBlQW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}