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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d67bc099bb9265ac0fffeef9c5392ce325d670040b14fff721eb2103feace3f' 
  AND token = '1U1pFUr0VPnXX47lGMUsHRA+9kQ4MVJqQl1K+FcKv1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}