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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2e0190d631d68e9e464bed50767e9a4729bfb38b7ba5d0ce5d662337d361bfe' 
  AND token = 'k/ygNkEyPSWe7f4qPwh3Coxw8imZayfzzl6xdnzsPZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}