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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0614088bf3c2fe94288a6a9c7a92c4edfb590b4f3ef67a4db8337b55e196a22' 
  AND token = 'FUW1BvkmVcMYsteEsq8jCGy1cwt86FHbNS9xNz+1jMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}