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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de7cc685b6b910db8966e40f2b7b57927212e3ab81012f913c9a4db808dca862' 
  AND token = 'dj1O8bIy2FTyd9WzZ6NPAbHpxMBj92/wv3xV7ksmkT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}