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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12049a22a9972ed4e8baf1405ead039b664e140d907513446783f087c012fdb6' 
  AND token = '5eQp37JcKM7D1cu/R5ouVEL7zVr0tpbb5pVWBLe4PXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}