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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '270afaa21e70e64485ef41c1682c86a8a507b7d35c41a768c2f4953521dfa364' 
  AND token = 'wnotX9u9DzE/1WwsdkLmOc3vMe8BCZ1bA7JNPoLibLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}