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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22cb023f99877f5b021f1aece0e6c099e429c8d2ad81926b797d02888dc616a2' 
  AND token = 'P4uiM+cT0VyxtRC0o4GT/6LHyohu9pIptoTzAMInx2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}