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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38a15f71daefb8b75a739efdb175a140affeef13fc5d372f12c97dbb1a1653a8' 
  AND token = 'Jo3h1Y7sgsVlu7zpxxPSb5WK8m4eMGVYq6N3jS7wqgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}