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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e9ccedaa512e4c61c7fa976d4e2e4779dafce85d2587e77c80476a8f62fc18' 
  AND token = 'xM6cgPNGg9lUIgMrhYp3NngbZ3UMWiza456rUOpXV00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}