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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78b387fa2be1fe74f62a5b16b2b68a2a32006bee2f46dadca6bf1a6f06cd15f' 
  AND token = 'aIX2++2fPZQV/7oIrnC5zqoF3YkCvaA5Ry7zgvkNo3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}