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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '022644ceb9a69e491d2bd09b1a3cc90ad6db6bd84faf38062a5e5720e736859a' 
  AND token = 'QYFu0QaVhaiIvJBLOAysUoxlFcy/DZeMpUrx1IHgchI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}