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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5666952d7905a21c944a410423a85d8776a1a97552ff05f1630ba9df00ea0c2e' 
  AND token = 'ffxnJ/B8Mp6OCpvu+b+n1IB77r0HSkrGb94m2a3hCzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}