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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80f7a2eceec9fd18ba82761e4508bab8d2e867a804d3f008c748aad37a64cc46' 
  AND token = '/SlHW+Y9o1iRTQSthYz+I93HsGI7e56MSDJF1DEBPF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}