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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1721b0e2da0fda907fb12b7c1657c089c9ff29b17ea0512db22bb9dc6df1335' 
  AND token = '07sQ5NwdDAwhslWerffD2vYhlGwqzXiEpGi+H7quJeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}