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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1605c404dbd7cccd69a712b9bf138ede7838884f5f7d1026a7781bcb99bccc5b' 
  AND token = 'DC010K7AUShL10EwlTicBvyaNk5eA8yHdgbUvaMdRQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}