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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ad14e43f6e4cc9be999d023c8e285a92c6950ac4f7b0c1f2139594942174590' 
  AND token = 'IsuNoWhObehl57btTB8kK7rffTmWD3C9CrIRGHpCvN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}