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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bed5193e187f92fa6ce659053a21dda7d06fa0337a039d03e1f315f581676f6a' 
  AND token = 'z9ISd7uhfzdVwXBPanGc2BwYi8BuHnS/t8nA0XP4dJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}