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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25c4977465910a38290476fa3767b29900cda5f99b908c7be271e399c1123363' 
  AND token = 'VzH9+UhuoT+JWgzwf3+1JO2cNYbhd+UDDPAp8DC2r0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}