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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4441fdb05a7936bfb2a3aeaeddff5882e6ada70da60f374a8a532264d989430' 
  AND token = '7Id0k/HcU6AF5YrdhaOIGLccZQHlTxD9Yk55BsYWnbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}