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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7ea6dfdeaf2ae6d59cb31008fe0f68a349c461af8894a8201ff97049821c22' 
  AND token = 'XDQ2wv9gzySsPlTU8yFiIoKIwTgif8u+5hinLA7aqgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}