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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c605ded5aa7c3e08ebf9e35f0847f41dc47306de67ec859d370d5eab9331632b' 
  AND token = 'v2sjg6hN2MqTdfTbxMnzK3a1RxsDqHkMngf7Jfr3+Gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}