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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74747a0a2a37cf5649733edfb8a42c2b679f498f41771543073aa6508dfac3d4' 
  AND token = 'Z0lwGSBQsHX81MVZRMj8gaZ5t3VDuEmodcorFHYy4Q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}