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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e9267f3213a51b22ca4bb716c6124e8db6f76aebee2895a5f9fc26f4b4bd268' 
  AND token = '1+0d9TxQVEIB0t0tIbw/8qPshf62e/t9PmMiUUeArpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}