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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b041d593110f5c5fd4c6714f44008c09eff49d713d670b0ea8b900c043e9014' 
  AND token = '5nh+cK/prEHBbkvrjOAUs3OdZdg5u0dpGkwwvpoVNEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}