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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da5ad2e47139ef9cc3b8d22e6994df52465b175fdc4763856e999ece62e3b260' 
  AND token = 'v7G6sRtYRtOo0tbs/I4CWDt2Sbz5oeFz9ullUOLD87Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}