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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c3f3e152a09aeee218baaa85c2308e87c0d18ab3eb5ee1f6eb1145c8cc5712c' 
  AND token = 'IyEjbyyNFSnIbPk3/Fx4qkrxTUe0+PezjN2sgt/8vYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}