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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d988ada8004013d6cd837a1b004d2280049652cebf09a4c373579c765cf882' 
  AND token = 'cPe1952VQX94QlyPzz5NrzRkqKPI/caf7szp6KQ77Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}