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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68f79407c4983294b89fea9b328689060947dd539d9bcffdf70d92cf6bdc8665' 
  AND token = 'oZDQN8V/FLicT2IhlLwwjfIFIz6wLGAr1QIYgE4y6Q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}