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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2321ceda0823d1a43b4871151a168b1470190c8f188a99de6ef9b61a99cbbc85' 
  AND token = 'jN6mVpFr9YDaFRP6q0zAs2jiFe2HKB8fDBYiSTRJrIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}