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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f3b3686bdd6160d7bf68f2991cd51d4489aa2301106cac67bfa417a0d4b0b18' 
  AND token = '2fVeOSNYYR4+Kwxi4Z368caNVuEA+rD/uWd/4uGrbWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}