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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0b0063bdef80358847e83203d4a0243904940f83569bced5e7254058afc8f5b' 
  AND token = 'z8DA9FYwn6cgvlbpCPERfBWDgidmHabUsVSMiQi+re0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}