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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58dd52b1aee87a11c20491b8f42d8f066e18c8e27653f33638f22d80a35f0453' 
  AND token = 'ZWufL/pV+uEwGg20xh8mePEabBm/ZqDOtmD45sW/JeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}