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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fcd2a9d85d055653fc792946a192bf018e87a132e50a3c0b0a0716aab1c079c' 
  AND token = 'V4mJzNSaIszoDKYRiQAENmoNrgRyTzwDfj2fzgqbopg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}