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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0116479008a6c5e4995423833d7c80ddcec4e2d23a3e789566250c67614b0d4' 
  AND token = 'rQQmMnffKp9PywUu+R7tEl5SyMyksJSw7Z3rCjaz+5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}