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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f372eababc3708a0183533f33e98f4d2b96be6b7cf7af4b2001ee182225574a' 
  AND token = 'Tsc5CjIFD4swA/h8opHTz4DNuHbPBd0jUeNcOmfd66M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}