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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e317fe598a4c75e1b46dbee26ef6d63749049033d7f0381eee2e1c362e66bf56' 
  AND token = 'ecIxex6L6Cs/zqMNn7yS7GovWNwhUcA5UfSVTGy1zH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}