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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e01490423a81d72e2b9f413ffceeff6d4bb4d560a28d7475db0fb6996610016a' 
  AND token = 'GrAfmt+mLzsrOR/HhKjSzUQGNIJ0l0lVzr+3CnAJEb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}