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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1178e17107c43362ec55be7daab11d05ed26f5d9a63e8b7f02d1c5f058fa76c1' 
  AND token = 'fM0tO7J7gWZ3E/42nRYM2SBAPZTM5ODGIXSA9XpkJqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}